New England Biolabs - Where science is the priority
In today's world, the molecular biology industry demands nothing less than the very best that science has to offer. There is no room for compromise. At New England Biolabs, we understand this fact. For over 25 years, we have led the industry in the discovery and production of enzymes for molecular biology applications. And through our extensive efforts in the cloning and overexpression of restriction/modification systems, we have set the standards for quality and price.
Why choose a recombinant enzyme from NEB?
At New England Biolabs, enzyme production is linked to basic research in the cloning and overexpression of restriction/modification enzyme systems. Our focus on providing the largest selection of recombinant enzymes has resulted in lower $/unit cost and improved purity and consistency of product. We are the only company which continues an aggressive research program in the cloning and overexpression of these essential reagents. Presently, over 120 recombinant restriction endonucleases are available from NEB, as well as numerous recombinant DNA and protein modifying enzymes.
Purity
Once an enzyme system is cloned, the choice of expression vector and strain background allows tight control over the production environment. For restriction endonucleases, this eliminates enzymes known to contaminate native preparations. Although our recombinant enzymes and native enzymes are manufactured to meet the same rigorous quality control standards, it is recombinant enzymes that produce a more pure product with less processing time.
Consistency
Typically, the yields obtained for recombinant and overexpressed enzymes are significantly larger than those produced by native strains. Production of larger lots means greater product consistency and less lot-to-lot variation. Further, this large lot capability is ideal for customers that have a need for bulk quantities of enzymes. It simplifies their quality assurance procedures by reducing the time and effort normally spent qualifying enzymes supplied from different lots.
Expertise
NEB focuses on the analysis of restriction/modification systems at the molecular level. Our goal is to understand the regulation of these specialized systems and how they interact with DNA. This expertise is available to our customers as part of the NEB commitment to customer service.
Innovative Product Development
at NEB includes the GPS*-1 Genome Priming System, a transposon-based technology to generate sequencing templates by placing universal priming sites into target DNA at random locations, and Impact-CN, a one-step protein purification system that allows purification of biologically active recombinant proteins in a single chromatographic step.
New England Biolabs GmbH
New England Biolabs GmbH is the NEB service hub for Central Europe. From our location in Frankfurt we serve scientists and industry customers in Germany, Austria and Eastern Europe.
Our recent move to the Technology-Park in Frankfurt-Höchst enables us to provide customized service beyond everyday experience. The quality of our personalized services, as well as our ability to deliver high quality products with unsurpassed consistency, guarantee our partners a valuable advantage in their research activities.
New England Biolabs GmbH is also the source for products from Cell Signaling Technology, a new company from NEB. CST being a leading producer of reagents for cell signal transduction research.