Epigenetics

EpiMark DNA Enrichment Kit

EpiMark 5-mC and 5-hmC Analysis Kit

EpiMark Bisulfite Conversion and Hot Start DNA Polymerase

Restriction Enzymes for Epigenetics

Histones and EpiMark Nucleosome Assembly Kit

Methyl-
transferases for Epigenetics

Control DNA

ChIP

For over 35 years, New England Biolabs, Inc. has been committed to understanding the mechanisms of restriction and methylation of DNA. This expertise in enzymology has recently led to the development of a suite of new reagents validated in epigenetic applications. EpiMark™ validated reagents simplify epigenetics research and expand the potential for biomarker discovery. This growing line of reagents and kits includes:

• The EpiMark™ Methylated DNA Enrichment Kit  to enrich double-stranded methyl-Cpg from fragmented genomic DNA with as little as 5 ng of input DNA 


• The EpiMark Bisulfite Conversion Kit to detect methylated cytosine via the conversion of unmodified cytosines to uracil 


• The EpiMark™ Hot Start Taq DNA Polymerase -  to amplify bisulfite-treated samples 


• TheEpiMark™ 5-mC and 5-hmC Analysis Kit  for locus-specific identification and quantification of 5-hydroxymethylcytosine 


• A novel family of methylation-dependent restriction endonucleases and enzymes with differential sensitivity to methylation, useful for mapping epigenetic modifications


• Highly purified, recombinant histones for substrates in purification and characterization of histone modification enzymes


• DNA methyltransferases to generate methylated DNA at specific sites for gene expression studies


• Protein methyltransferases for specific histone modification required by gene regulation studies


• Modified and unmodified genomic DNAs to use as controls

E3: Engaging Epigenetics Experts

Introducing an online community to connect epigenetics researchers, publications and discoveries.

Join Now!

For detailed up-to-date information regarding all available EpiMark Reagents for Epigenetic Research as well as interesting background information on epigenetics, please request your free copy of the brochure "Epigenetics - Understanding Histone DNA Modifikation"